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Anticorps Polyclonal de lapin anti-DNase I

DNase I Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16659-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using DNase I Polyclonal antibody (16659-1-AP)

    WB analysis using 16659-1-AP (same clone as 16659-1-PBS)

    human urine sample were subjected to SDS PAGE followed by western blot with 16659-1-AP (DNase I antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16659-1-PBS in a different storage buffer formulation.

Informations sur le produit

16659-1-PBS cible DNase I dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène DNase I Protéine recombinante Ag10117
Nom complet deoxyribonuclease I
Masse moléculaire calculée 282 aa, 31 kDa
Poids moléculaire observé 31-40 kDa
Numéro d’acquisition GenBankBC029437
Symbole du gène DNASE1
Identification du gène (NCBI) 1773
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Deoxyribonuclease I (DNase I), also known as DNL1 and DRNI, belongs to the DNase I family. DNase I is a DNA-digestive glycoprotein that cleaves both single- and double stranded DNA through hydrolysis of the phosphodiester bond. In humans, the DNase I enzyme is primarily secreted by the pancreas, parotid, and pituitary glands into the digestive system and bloodstream. Since DNase I is ubiquitously expressed in human tissues, it is thought to play a similar anti-autoimmune role in other organs as well (PMID: 21806320). The calculated molecular weight of DNase I is 31 kDa. Sometimes higher molecular weight around 40 kDa can also be observed, which is caused by glycosylation (PMID: 34329318).

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