Anticorps Monoclonal anti-DOCK1

DOCK1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1C3F12

N° de cat : 67296-1-PBS

Synonymes

ced5, dedicator of cytokinesis 1, DOCK1, DOCK180

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Galerie de données de validation

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  WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67296-1-PBS cible DOCK1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: DOCK1 Protéine recombinante Ag18069
• Nom complet: dedicator of cytokinesis 1
• Masse moléculaire calculée: 1865 aa, 215 kDa
• Poids moléculaire observé: 215 kDa
• Numéro d’acquisition GenBank: BC146857
• Symbole du gène: DOCK1
• Identification du gène (NCBI): 1793
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1

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