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Anticorps Polyclonal de lapin anti-DOCK4

DOCK4 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27151-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of HEK-293T cells using DOCK4 Polyclonal antibody (27151-1-AP)

    WB analysis of HEK-293T using 27151-1-AP (same clone as 27151-1-PBS)

    HEK-293T cells were subjected to SDS PAGE followed by western blot with 27151-1-AP (DOCK4 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27151-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using DOCK4 Polyclonal antibody (27151-1-AP)

    IF Staining of HeLa using 27151-1-AP (same clone as 27151-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using 27151-1-AP (DOCK4 antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27151-1-PBS in a different storage buffer formulation.

Informations sur le produit

27151-1-PBS cible DOCK4 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène DOCK4 Protéine recombinante Ag25946
Nom complet dedicator of cytokinesis 4
Masse moléculaire calculée 2011 aa, 230 kDa
Poids moléculaire observé 225 kDa
Numéro d’acquisition GenBankBC117689
Symbole du gène DOCK4
Identification du gène (NCBI) 9732
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DOCK4, originally identified as a product of a gene which is deleted during tumor progression, is a member of DOCK180 family proteins. Dock4 has been found recently to be associated with several neuropsychiatric diseases, including autism, dyslexia, and schizophrenia. Multiple studies in fibroblasts then confirmed that Dock4 is capable of controlling cell migration by transducing several upstream signals, such as Wnt, platelet-derived growth factor, and RhoG, toward activation of Rac1. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers.

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