Anticorps Recombinant de lapin anti-DPP4/CD26

DPP4/CD26 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242045C1

N° de cat : 98261-1-PBS

Synonymes

CD26, ADCP-2, ADCP2, ADCP 2, ADABP

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Galerie de données de validation

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  FC experiment of human PBMCs using 98261-1-RR (same clone as 98261-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DPP4/CD26 Rabbit Recombinant Antibody (98261-1-RR, Clone: 242045C1) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (APC-65569, Clone: OKT3). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98261-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98261-1-RR (same clone as 98261-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human DPP4/CD26 Rabbit Recombinant Antibody (98261-1-RR, Clone: 242045C1) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98261-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98261-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98261-1-RR against Human DPP4/CD26 were performed. The affinity constant is 2.22 nM.

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Informations sur le produit

98261-1-PBS cible DPP4/CD26 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: dipeptidyl-peptidase 4
• Masse moléculaire calculée: 88 kDa
• Numéro d’acquisition GenBank: BC013329
• Symbole du gène: DPP4
• Identification du gène (NCBI): 1803
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD26, also known as DPP4 (dipeptidyl peptidase-4), is a 110 kDa type II cell-surface glycoprotein widely expressed on T cells, activated B cells, activated NK cells and myeloid cells as well as on epithelial cells, fibroblasts, mesothelium, and endothelial cells of a variety of tissues (PMID:33777580; 26919392). It has ecto-enzyme activity in its extracellular domain and cleaves amino-terminal dipeptides with either L-proline or L-alanine at the penultimate position (PMID: 9553764). CD26 plays roles in diverse biological processes such as immunoregulation, glucose homeostasis, and tumorigenesis (PMID: 33777580).

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