Anticorps Polyclonal de lapin anti-DRD1

• Phare
• Validé par KD/KO

DRD1 Polyclonal Antibody for WB, IF-Fro, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF-Fro, ELISA

Conjugaison

Non conjugué

N° de cat : 17934-1-PBS

Synonymes

D(1A) dopamine receptor, DADR, Dopamine D1 receptor, dopamine receptor D1

---

Galerie de données de validation

• 

  WB analysis of mouse brain using 17934-1-AP (same clone as 17934-1-PBS)

  37°C incubated mouse brain tissue were subjected to SDS PAGE followed by western blot with 17934-1-AP (DRD1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17934-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse brain using 17934-1-AP (same clone as 17934-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed frozen OCT-embedded mouse brain tissue using DRD1 antibody (17934-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 17934-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

17934-1-PBS cible DRD1 dans les applications de WB, IF-Fro, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DRD1 Protéine recombinante Ag12366
• Nom complet: dopamine receptor D1
• Masse moléculaire calculée: 446 aa, 49 kDa
• Poids moléculaire observé: 50-75 kDa
• Numéro d’acquisition GenBank: BC074978
• Symbole du gène: DRD1
• Identification du gène (NCBI): 1812
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Dopamine is a neurotransmitter that plays a crucial role in physical and mental health, such as cardiovascular, hormonal, renal, and central nervous systems (PMID: 29220802). Five subtypes of mammalian dopamine receptors are grouped into two classes, the D1- and D2-like classes. The D1-like class includes D1 and D5 receptors whereas the D2-like class includes D2, D3, D4 subtypes (PMID: 9457173). Dopamine receptor D1 (DRD1) is the most abundant form of dopamine receptor in the central nervous system. DRD1 stimulates adenylate cyclase, modulates D2 receptor activity, regulates neuron growth and differentiation, and mediates several behavioral responses (PMID: 1977312). DRD1 has a calculated molecular weight of 49 kDa, larger apparent molecular weight of 60-80 kDa may be due to glycosylation (PMID: 1281547; 23821371).

{{ptg:RelatedPrimaryAntibodies}}