Anticorps Polyclonal de lapin anti-DRD4

DRD4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, porc, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28094-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse brain using 28094-1-AP (same clone as 28094-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 28094-1-AP (DRD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28094-1-PBS in a different storage buffer formulation.

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  WB analysis of pig brain using 28094-1-AP (same clone as 28094-1-PBS)

  pig brain tissue were subjected to SDS PAGE followed by western blot with 28094-1-AP (DRD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28094-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28094-1-PBS cible DRD4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, souris

• Réactivité: Humain, porc, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DRD4 Protéine recombinante Ag26930
• Nom complet: dopamine receptor D4
• Masse moléculaire calculée: 44 kDa
• Poids moléculaire observé: 40-44 kDa
• Numéro d’acquisition GenBank: NM_000797
• Symbole du gène: DRD4
• Identification du gène (NCBI): 1815
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The family of dopamine receptors (DRs) includes five G protein-coupled receptors (GPCRs)-DRD1, DRD2, DRD3, DRD4 and DRD5-with different anatomical distribution, expression levels, dopamine affinity, signal transduction, and effector targets (PMID:36523297). DRD4 (dopamine receptor D4) influences the postsynaptic action of dopamine and is implicated in many neurological processes, exhibits polymorphism and is one of the most studied genes in connection with psychiatric disorders (PMID:21873960). Moreover, DRD4 modulate glucose metabolism, and protect neurocytes from anoxia/reoxygenation (A/R) injury. Thus, DRD4 might regulate myocardial I/R injury in association with GLUT4-mediated glucose metabolism (PMID:33584304).

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