Anticorps Recombinant de lapin anti-DSC2

DSC2 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241084G9

N° de cat : 84985-1-PBS

Synonymes

Desmocollin 2, Desmocollin 3, CDHF2, Cadherin family member 2, ARVD11

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Galerie de données de validation

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  IF Staining of Caco-2 using 84985-1-RR (same clone as 84985-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed Caco-2 cells using DSC2 antibody (84985-1-RR, Clone: 241084G9 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84985-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84985-1-PBS cible DSC2 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: DSC2 Protéine recombinante Ag4956
• Nom complet: desmocollin 2
• Masse moléculaire calculée: 100 kDa
• Numéro d’acquisition GenBank: BC063291
• Symbole du gène: Desmocollin 2
• Identification du gène (NCBI): 1824
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelial and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in the DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.

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