Anticorps Polyclonal de lapin anti-DTX4

• Phare
• Validé par KD/KO

DTX4 Polyclonal Antibody for WB, IF/ICC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF/ICC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25222-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse kidney using 25222-1-AP (same clone as 25222-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 25222-1-AP (DTX4 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25222-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse kidney using 25222-1-AP (same clone as 25222-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 25222-1-AP (DTX4 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25222-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse embryo using 25222-1-AP (same clone as 25222-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse embryo tissue using 25222-1-AP (DTX4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 25222-1-PBS in a different storage buffer formulation.

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  IF Staining of HEK-293 using 25222-1-AP (same clone as 25222-1-PBS)

  Immunofluorescent analysis of HEK-293 cells using 25222-1-AP (DTX4 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 25222-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25222-1-PBS cible DTX4 dans les applications de WB, IF/ICC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DTX4 Protéine recombinante Ag18415
• Nom complet: deltex homolog 4 (Drosophila)
• Masse moléculaire calculée: 619 aa, 67 kDa
• Poids moléculaire observé: 67-70 kDa
• Numéro d’acquisition GenBank: BC119011
• Symbole du gène: DTX4
• Identification du gène (NCBI): 23220
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DTX4, also named as KIAA0937, RNF155, is a 619 amino acid protein, which belongs to the Deltex family. DTX4 as a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX4 functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

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