Anticorps Polyclonal de lapin anti-DUSP2

• Phare
• Validé par KD/KO

DUSP2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27327-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis of A549 using 27327-1-AP (same clone as 27327-1-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 27327-1-AP (DUSP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27327-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 27327-1-AP (same clone as 27327-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27327-1-AP (DUSP2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27327-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 27327-1-AP (same clone as 27327-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 27327-1-AP (DUSP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27327-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

27327-1-PBS cible DUSP2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DUSP2 Protéine recombinante Ag25380
• Nom complet: dual specificity phosphatase 2
• Masse moléculaire calculée: 34 kDa
• Poids moléculaire observé: 34 kDa
• Numéro d’acquisition GenBank: BC007771
• Symbole du gène: DUSP2
• Identification du gène (NCBI): 1844
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DUSP2 belongs to the sub-family of nuclear specific DUSPs that includes DUSP1, 4 and 5. DUSP2 is highly expressed in immune cells, in particular, of patients with inflammatory arthritis, such as in rheumatoid arthritis (RA), and Dusp2 knockout mice present a significant reduction in inflammatory responses. It has been demonstrated that DUSP2 is a downstream target of the tumor suppressor p53 that is required for the cellular response to oxidative stress. DUSP2 is also involved in transcription factor E2F1-mediated apoptotic signaling. Like other members of the DUSP family, DUSP2 interacts with MAPKs; However, the target protein for its phosphatase activity is controversial.

{{ptg:RelatedPrimaryAntibodies}}