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Anticorps Recombinant de lapin anti-DYNC1H1

DYNC1H1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242706B12

N° de cat : 85397-4-PBS

Synonymes

DYNC1H 1

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using DYNC1H1 Recombinant antibody (85397-4-RR)

    WB analysis using 85397-4-RR (same clone as 85397-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85397-4-RR (KIAA0325 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85397-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85397-4-PBS

    Affinity and Kinetic Characterization of 85397-4-PBS

    Biolayer interferometry (BLl) kinetic assays of 85397-4-RR against Human DYNC1H1 were performed. The affinity constant is below 1 pM.

Informations sur le produit

85397-4-PBS cible DYNC1H1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène DYNC1H1 Protéine recombinante Ag2999
Nom complet dynein, cytoplasmic 1, heavy chain 1
Masse moléculaire calculée 4646 aa, 532 kDa
Poids moléculaire observé532 kDa
Numéro d’acquisition GenBankBC021297
Symbole du gène DYNC1H1
Identification du gène (NCBI) 1778
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Dyneins are a group of microtubule-activated ATPases that convert chemical energy into mechanical energy. It can be divided into 2 large subgroups, namely, the axonemal and cytoplasmic dyneins. The conventional cytoplasmic dynein comprises 2 heavy chain polypeptides and several intermediate and light chains. DYNC1H1 is a cytoplasmic dynein and belongs to the dynein heavy chain family. It acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. DYNC1H1 has been implicated in the degeneration of dopaminergic neuron axons and motor neurons in PD patients.

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