Anticorps Polyclonal de lapin anti-DYNC1LI2

DYNC1LI2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18885-1-PBS

Synonymes

LIC53/55, LIC-2, LIC2, LIC 2, DNCLI2

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Galerie de données de validation

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  WB analysis of mouse testis using 18885-1-AP (same clone as 18885-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat kidney using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18885-1-PBS cible DYNC1LI2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DYNC1LI2 Protéine recombinante Ag13452
• Nom complet: dynein, cytoplasmic 1, light intermediate chain 2
• Masse moléculaire calculée: 492 aa, 54 kDa
• Poids moléculaire observé: 48-50 kDa
• Numéro d’acquisition GenBank: BC025959
• Symbole du gène: DYNC1LI2
• Identification du gène (NCBI): 1783
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cytoplasmic dynein is a microtubule-associated motor protein. DYNC1LI2 (Cytoplasmic dynein 1 light intermediate chain 2), also known as LIC2, belongs to the dynein light intermediate chain family. DYNC1LI2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. It may play a role in binding dynein to membranous organelles or chromosomes. Northern blot analysis of rat tissues detected high expression of DYNC1LI2 in skeletal muscle, testis, heart, lung, and brain, and lower expression in liver, kidney, and spleen (PMID: 7738094).

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