Anticorps Monoclonal anti-Decorin

Decorin Monoclonal Antibody for WB, IF/ICC, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc

Applications

WB, IF/ICC, ELISA

Conjugaison

Non conjugué

CloneNo.

3A4E4

N° de cat : 66847-1-PBS

Synonymes

DCN, PG40, PG S2, DSPG2, CSCD

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Galerie de données de validation

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  WB analysis of pig cartilage using 66847-1-Ig (same clone as 66847-1-PBS)

  pig cartilage tissue were subjected to SDS PAGE followed by western blot with 66847-1-Ig (Decorin antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66847-1-PBS in a different storage buffer formulation.

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  IF Staining of BxPC-3 using 66847-1-Ig (same clone as 66847-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed BxPC-3 cells using Decorin antibody (66847-1-Ig, Clone: 3A4E4 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 66847-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66847-1-PBS cible Decorin dans les applications de WB, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain, porc

• Réactivité: Humain, porc
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Decorin Protéine recombinante Ag6275
• Nom complet: decorin
• Masse moléculaire calculée: 359 aa, 40 kDa
• Poids moléculaire observé: 40 kDa, 100 kDa
• Numéro d’acquisition GenBank: BC005322
• Symbole du gène: Decorin
• Identification du gène (NCBI): 1634
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Decorin is a member of the small leucine-rich proteoglycan family of proteins. Decorin interacts with type I collagen fibrils, thereby influencing the kinetics of fibril formation and the distance between adjacent collagen fibrils. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis.

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