Anticorps Monoclonal anti-Dynamitin (1-401 AA)

Dynamitin (1-401 AA) Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG3

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2B9A5

N° de cat : 60257-1-PBS

Synonymes

DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin, Dynamitin (1-401 AA), p50 dynamitin, RBP50

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Galerie de données de validation

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  WB analysis of human brain using 60257-1-Ig (same clone as 60257-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 60257-1-Ig (Dynamitin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60257-1-PBS cible Dynamitin (1-401 AA) dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG3
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Dynamitin (1-401 AA) Protéine recombinante Ag1902
• Nom complet: dynactin 2 (p50)
• Masse moléculaire calculée: 401 aa, 44 kDa
• Poids moléculaire observé: 52+150 kDa
• Numéro d’acquisition GenBank: BC014083
• Symbole du gène: Dynamitin
• Identification du gène (NCBI): 10540
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.

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