Anticorps Recombinant de lapin anti-E-selectin/CD62E

E-selectin/CD62E Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240700D4

N° de cat : 98065-1-RR

Synonymes

CD62E, E-selectin, 240700D4, E selectin, Elam

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Galerie de données de validation

• 

  FC experiment of bEnd.3 using 98065-1-RR

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug Anti-Mouse E-selectin/CD62E Rabbit Recombinant Antibody (98065-1-RR, Clone:240700D4) (red) or isotype control (blue) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98065-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98065-1-RR against Mouse E-selectin/CD62E were performed. The affinity constant is 4.40 nM.

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Applications testées

• Résultats positifs en cytométrie: cellules bEnd.3,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98065-1-RR cible E-selectin/CD62E dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: selectin, endothelial cell
• Masse moléculaire calculée: 67KD
• Numéro d’acquisition GenBank: NM_011345.2
• Symbole du gène: Sele
• Identification du gène (NCBI): 20339
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

E-selectin, also known as CD62E or ELAM-1, is a member of the selectin family of adhesion molecules that also includes L-selectin and P-selectin. E-selectin is an inducible endothelial cell surface molecule. Its expression on endothelial cells is transcriptionally upregulated by various proinflammatory substances such as IL-1, TNFα and lipopolysaccharide (LPS). Besides, it can be secreted by endothelial cells, and can be detected in a soluble form (sE-selectin) in serum. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. (PMID: 2827173; 1382417; 8943958)

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