Anticorps Recombinant de lapin anti-E-selectin/CD62E

E-selectin/CD62E Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

240700D4

N° de cat : FITC-98065

Synonymes

CD62E, E-selectin, 240700D4, E selectin, Elam

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Galerie de données de validation

• 

  FC experiment of bEnd.3 using FITC-98065

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug FITC Plus Anti-Mouse E-selectin/CD62E Rabbit RecAb (FITC-98065, Clone:240700D4) (red), or 0.25 ug FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules bEnd.3,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98065 cible E-selectin/CD62E dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: E-selectin/CD62E Protéine recombinante Eg0610
• Nom complet: selectin, endothelial cell
• Masse moléculaire calculée: 67KD
• Numéro d’acquisition GenBank: NM_011345.2
• Symbole du gène: Sele
• Identification du gène (NCBI): 20339
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

E-selectin, also known as CD62E or ELAM-1, is a member of the selectin family of adhesion molecules that also includes L-selectin and P-selectin. E-selectin is an inducible endothelial cell surface molecule. Its expression on endothelial cells is transcriptionally upregulated by various proinflammatory substances such as IL-1, TNFα and lipopolysaccharide (LPS). Besides, it can be secreted by endothelial cells, and can be detected in a soluble form (sE-selectin) in serum. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. (PMID: 2827173; 1382417; 8943958)

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