Anticorps Polyclonal de lapin anti-E2F6

E2F6 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10691-1-PBS

Synonymes

E2F-6, E2F 6

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Galerie de données de validation

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  WB analysis using 10691-1-AP (same clone as 10691-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10691-1-AP (E2F6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10691-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10691-1-PBS cible E2F6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: E2F6 Protéine recombinante Ag1029
• Nom complet: E2F transcription factor 6
• Masse moléculaire calculée: 32 kDa
• Poids moléculaire observé: 37 kDa
• Numéro d’acquisition GenBank: BC008348
• Symbole du gène: E2F6
• Identification du gène (NCBI): 1876
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

E2F6 is a member of the E2F family of transcription factors, which play important roles in cell cycle regulation and gene expression. E2F6 is highly expressed in many types of cancer and is associated with poor prognosis. It is involved in the regulation of cell proliferation and can promote tumor growth. E2F6 knockdown significantly reduces the proliferative ability of glioma cells (PMID: 38071912). Additionally, E2F6 is related to immune activation markers, tumor immune cell infiltration, and immune regulators, making it a potential biomarker for predicting the response to cancer immunotherapy.

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