Anticorps Monoclonal anti-EAAT2

EAAT2 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA, Sample test

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

1C8D10

N° de cat : 67083-1-PBS

Synonymes

GLT1, SLC1A2, 1C8D10, GLT 1, Sodium-dependent glutamate/aspartate transporter 2

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Galerie de données de validation

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  WB analysis using 67083-1-Ig (same clone as 67083-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67083-1-Ig (SLC1A2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67083-1-PBS in a different storage buffer formulation.

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  Sample test of MP51374-1

  Sample test of MP51374-1, SLC1A2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67083-2-PBS. Detection antibody: 67083-1-PBS.

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  Cytometric bead array standard curve of MP51374-1

  Cytometric bead array standard curve of MP51374-1, SLC1A2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67083-2-PBS. Detection antibody: 67083-1-PBS. Standard:Ag19816. Range: 0.098-100 ng/mL.

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Informations sur le produit

67083-1-PBS cible EAAT2 dans les applications de WB, Cytometric bead array, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: EAAT2 Protéine recombinante Ag19816
• Nom complet: solute carrier family 1 (glial high affinity glutamate transporter), member 2
• Masse moléculaire calculée: 574 aa, 62 kDa
• Poids moléculaire observé: 60-70 kDa
• Numéro d’acquisition GenBank: BC132768
• Symbole du gène: EAAT2
• Identification du gène (NCBI): 6506
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

EAAT2 (also known as GLT-1), is encoded by SLC1A2 and is a glutamate transporter which can clear the majority of extracellular glutamate in brain and prevent brain seizures.Three isoforms of EAAT2 exist due to the alternative splicing. In addition to the 65-70 kDa monomer form, 130-150 kDa dimer of EAAT2 can also be observed on SDS-PAGE.(PMID: 22114258)

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