Anticorps Monoclonal anti-EBI3/IL-27B

EBI3/IL-27B Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1F3H10

N° de cat : 66354-1-PBS

Synonymes

EBI3, 1F3H10, EBV induced gene 3 protein, EBV-induced gene 3 protein, Epstein Barr virus induced 3

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Galerie de données de validation

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  WB analysis of human spleen using 66354-1-Ig (same clone as 66354-1-PBS)

  human spleen tissue were subjected to SDS PAGE followed by western blot with 66354-1-Ig (EBI3 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66354-1-PBS in a different storage buffer formulation.

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  WB analysis of rat spleen using 66354-1-Ig (same clone as 66354-1-PBS)

  rat spleen tissue were subjected to SDS PAGE followed by western blot with 66354-1-Ig (EBI3 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66354-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66354-1-PBS cible EBI3/IL-27B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat

• Réactivité: Humain, porc, rat
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: EBI3/IL-27B Protéine recombinante Ag3051
• Nom complet: Epstein-Barr virus induced 3
• Masse moléculaire calculée: 229 aa, 25 kDa
• Poids moléculaire observé: 34 kDa
• Numéro d’acquisition GenBank: BC015364
• Symbole du gène: EBI3
• Identification du gène (NCBI): 10148
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

EBI3, a 34-kDa secreted glycoprotein, is a subunit in 2 distinct heterodimeric cytokines: IL-27 and IL-35. IL-27, composed of p28 (IL-27) and EBI3, can trigger signaling in T cells, B cells, and myeloid cells. IL-35, composed of EBI3 and the ubiquitously expressed p35 subunit of IL-12, is an inhibitory cytokine involved in regulatory T-cell function. EBI3 plays a role in regulating cell-mediated immune responses. (PMID: 8551575; 18033300; 17874423; 21931777)

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