Anticorps Polyclonal de lapin anti-EDARADD

EDARADD Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32485-1-PBS

Synonymes

Ectodysplasin-A receptor-associated adapter protein, EDAR-associated death domain protein, Protein crinkled homolog

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Galerie de données de validation

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  WB analysis using 32485-1-AP (same clone as 32485-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32485-1-AP (EDARADD antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32485-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32485-1-PBS cible EDARADD dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: EDARADD Protéine recombinante Ag38064
• Nom complet: EDAR-associated death domain
• Poids moléculaire observé: 24 kDa
• Numéro d’acquisition GenBank: BC128082
• Symbole du gène: EDARADD
• Identification du gène (NCBI): 128178
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

EDARADD (EDAR-associated death domain) is an adaptor protein that mediates the interaction between the extracellular Ectodysplasin A receptor (EDAR) and intracellular signaling components, orchestrating a series of downstream events that regulate key biological processes such as cell proliferation, differentiation, and apoptosis. EDARADD is a 25 KDa death domain-containing adaptor protein. EDARADD was shown to interact with TRAF1, -2 and -3 as well as with TAB2 (TAK1-binding protein 2) and is therefore likely to be responsible for coupling receptor activation with engagement of the NF-κB pathway (PMID: 23845861).

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