Anticorps Polyclonal de lapin anti-EFCAB4A

• Phare
• Validé par KD/KO

EFCAB4A Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32115-1-PBS

Synonymes

Ca2+ Release-Activated Ca2+ (CRAC) Channel Regulator 2B, Calcium Release Activated Channel Regulator 2B, Calcium release-activated calcium channel regulator 2B, Calcium release-activated channel regulator 2B, CRAC channel regulator 2B

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Galerie de données de validation

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  WB analysis using 32115-1-AP (same clone as 32115-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32115-1-AP (EFCAB4A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32115-1-PBS in a different storage buffer formulation.

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  WB analysis of LNCaP using 32115-1-AP (same clone as 32115-1-PBS)

  WB result of EFCAB4A antibody (32115-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-EFCAB4A transfected LNCaP cells. This data was developed using the same antibody clone with 32115-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32115-1-PBS cible EFCAB4A dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: EFCAB4A Protéine recombinante Ag37031
• Nom complet: EF-hand calcium binding domain 4A
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC033196
• Symbole du gène: EFCAB4A
• Identification du gène (NCBI): 283229
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

EFCAB4A (EF-hand calcium-binding domain-containing protein 4A), also known as CRACR2B (calcium release-activated calcium channel regulator 2B), is a calcium-binding protein containing EF-hand structural domain. EFCAB4A is thought to play a key role in calcium bank-manipulated calcium endocytosis (SOCE) in T cells by regulating activation of CRAC (calcium release-activated calcium channel) channels. This protein may perform a similar function to EFCAB4B, which acts as a cytoplasmic calcium sensor that forms a complex with ORAI1 and STIM1 in the region of the junction between the endoplasmic reticulum and the plasma membrane. The EFCAB4A protein contains two EF-hand structural domains, which may be involved in calcium bank-manipulated calcium endocytosis.

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