Anticorps Monoclonal anti-EIF2AK2, PKR

EIF2AK2, PKR Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2A8A4

N° de cat : 66646-1-PBS

Synonymes

EIF2AK2, PKR, 2A8A4, EC:2.7.10.2, EC:2.7.11.1

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Galerie de données de validation

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  WB analysis using 66646-1-Ig (same clone as 66646-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66646-1-Ig (EIF2AK2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66646-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 66646-1-Ig (same clone as 66646-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 66646-1-Ig (EIF2AK2 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66646-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 66646-1-Ig (same clone as 66646-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 66646-1-Ig (EIF2AK2 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66646-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 66646-1-Ig (same clone as 66646-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66646-1-Ig (EIF2AK2 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66646-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 66646-1-Ig (same clone as 66646-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66646-1-Ig (EIF2AK2 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66646-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66646-1-PBS cible EIF2AK2, PKR dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: EIF2AK2, PKR Protéine recombinante Ag13010
• Nom complet: eukaryotic translation initiation factor 2-alpha kinase 2
• Masse moléculaire calculée: 551 aa, 62 kDa
• Poids moléculaire observé: 65-68 kDa
• Numéro d’acquisition GenBank: BC093676
• Symbole du gène: EIF2AK2
• Identification du gène (NCBI): 5610
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2, also known as PKR or PRKR) is an important component of the host innate immuneantiviral response.The product of the HSAEIF2AK2 gene is a 68 kDa protein that is ubiquitously expressed at low levels. The N-terminal part of this protein contains two dsRNA binding motifs (dsRBM) .The C-terminal EIF2S1 kinase domain includes 12 sub-domains that are conserved in several Species(PMID:16954046 ).This antibody is specific to EIF2AK2.

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