Anticorps Polyclonal de lapin anti-ELL2

• Phare
• Validé par KD/KO

ELL2 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12727-1-PBS

Synonymes

ELL 2

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Galerie de données de validation

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  WB analysis using 12727-1-AP (same clone as 12727-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12727-1-AP (ELL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12727-1-PBS in a different storage buffer formulation.

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  WB analysis using 12727-1-AP (same clone as 12727-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12727-1-AP (ELL2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12727-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 12727-1-AP (same clone as 12727-1-PBS)

  IP result of anti-ELL2 (IP:12727-1-AP, 4ug; Detection:12727-1-AP 1:300) with mouse brain tissue lysate 3440ug. This data was developed using the same antibody clone with 12727-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12727-1-PBS cible ELL2 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ELL2 Protéine recombinante Ag3428
• Nom complet: elongation factor, RNA polymerase II, 2
• Masse moléculaire calculée: 640 aa, 72 kDa
• Poids moléculaire observé: 72 kDa
• Numéro d’acquisition GenBank: BC028412
• Symbole du gène: ELL2
• Identification du gène (NCBI): 22936
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ELL2 (Elongation Factor for RNA Polymerase II 2) is a key transcriptional elongation factor that regulates RNA polymerase II (Pol II) during mRNA synthesis (PMID: 34265249). It belongs to the ELL gene family, which includes ELL1, ELL2, and ELL3, and plays a crucial role in controlling the elongation phase of transcription (PMID: 9108030). ELL2 is an androgen-responsive gene that is expressed by prostate epithelial cells and is frequently down-regulated in prostate cancer (PMID: 29179998).

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