Anticorps Recombinant de lapin anti-ELOVL4

ELOVL4 Recombinant Antibody for FC (Intra), ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC (Intra), ELISA

Conjugaison

Non conjugué

CloneNo.

240608A11

N° de cat : 84050-1-PBS

Synonymes

ELOVL fatty acid elongase 4, ELOVL FA elongase 4, EC:2.3.1.199, ADMD, 3-keto acyl-CoA synthase ELOVL4

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Galerie de données de validation

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  FC experiment of A431 using 84050-1-RR (same clone as 84050-1-PBS)

  1x10^6 A431 cells were intracellularly stained with 0.25 ug Elovl4 Recombinant Antibody (84050-1-RR, Clone:240608A11) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 84050-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84050-1-PBS cible ELOVL4 dans les applications de FC (Intra), ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
• Masse moléculaire calculée: 37 kDa
• Numéro d’acquisition GenBank: NM_022726
• Symbole du gène: ELOVL4
• Identification du gène (NCBI): 6785
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ELOVL4, also named as ADMD, STGD2 and STGD3, belongs to the ELO family. It is a component of the fatty acid elongation system. Elovl4 is involved in the biosynthesis of very long chain fatty acids. It seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. ELOVL4 may be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. Defects in ELOVL4 are the cause of Stargardt disease type 3 (STGD3). The antibody is specific to ELOVL4.

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