Anticorps Recombinant de lapin anti-ENPEP

ENPEP Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250659C1

N° de cat : 98489-3-PBS

Synonymes

Aminopeptidase A, AP-A, BP-1/6C3 antigen, CD249, EAP

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 98489-3-RR (same clone as 98489-3-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse ENPEP Rabbit RecAb (98489-3-RR, Clone:250659C1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were then stained with APC Anti-Mouse CD45R. Cells were not fixed. This data was developed using the same antibody clone with 98489-3-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98489-3-RR (same clone as 98489-3-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse ENPEP Rabbit RecAb (98489-3-RR, Clone: 250659C1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were then stained with APC Anti-Mouse CD45R. Cells were not fixed. This data was developed using the same antibody clone with 98489-3-PBS in a different storage buffer formulation.

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Informations sur le produit

98489-3-PBS cible ENPEP dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ENPEP Protéine recombinante Eg4233
• Nom complet: glutamyl aminopeptidase
• Masse moléculaire calculée: 108 kDa
• Numéro d’acquisition GenBank: NM_007934.3
• Symbole du gène: Enpep
• Identification du gène (NCBI): 13809
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

ENPEP is the gene encoding the protein glutamyl aminopeptidase, also known as aminopeptidase A (APA), human kidney differentiation antigen (gp160). A type 2 membrane zinc metalloenzyme, APA is a general-purpose protease that primarily serves to cleave the acidic N-terminal aspartate and glutamyl residues of a variety of peptides, most significantly angiotensin 2 (ANG2, ang1-8), cholecystokinin-8 (CCK8), and neurokinin A. The presence of Ca2+ augments both the enzymatic efficiency and specificity of APA, increasing its selectivity towards the aforementioned acidic amino acids. Conversely, in the absence of calcium, APA can bind a wider range of N-terminal neutral and basic amino acids, some of which are cleaved, while others bind without proteolysis.

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