Anticorps Polyclonal de lapin anti-ENPP3/CD203c

ENPP3/CD203c Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28303-1-PBS

Synonymes

ENPP3, B10, CD203c, E NPP 3, PD IBETA

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Galerie de données de validation

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  WB analysis using 28303-1-AP (same clone as 28303-1-PBS)

  rat small intestine tissue were subjected to SDS PAGE followed by western blot with 28303-1-AP (ENPP3/CD203c antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28303-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28303-1-PBS cible ENPP3/CD203c dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ENPP3/CD203c Protéine recombinante Ag28478
• Nom complet: ectonucleotide pyrophosphatase/phosphodiesterase 3
• Masse moléculaire calculée: 875 aa, 100 kDa
• Poids moléculaire observé: 120-150 kDa
• Numéro d’acquisition GenBank: BC146579
• Symbole du gène: ENPP3
• Identification du gène (NCBI): 5169
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ENPP3/CD203c is part of ectonucleotide pyrophosphatases/phosphodiesterase (ENPP) family and plays a role in various physiological processes. Increased levels of ENPP3 have been observed in conditions, such as clear cell renal cell carcinoma, bile duct carcinoma, and colorectal cancer, positioning ENPP3 as a potential tumor marker (PMID: 38749434). Mice harboring a point mutant of ENPP3 that specifically abolishes its cGAMP hydrolase activity are more resistant to both primary tumor growth and metastasis in certain cancers (PMID: 38149831). High molecular weight band is the glycosylated form of ENPP3 (PMID: 27665743, 30271993)

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