Anticorps Recombinant de lapin anti-ENPP3/CD203c

ENPP3/CD203c Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242965D11

N° de cat : 98490-2-PBS

Synonymes

ENPP3, B10, CD203c, E NPP 3, PD IBETA

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Galerie de données de validation

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  FC experiment of human PBMCs using 98490-2-RR (same clone as 98490-2-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ENPP3/CD203c Rabbit RecAb (98490-2-RR, Clone: 242965D11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human IL3RA/CD123 Rabbit Recombinant Antibody (CL647-98107, Clone: 241268E3). Cells were not fixed. This data was developed using the same antibody clone with 98490-2-PBS in a different storage buffer formulation.

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Informations sur le produit

98490-2-PBS cible ENPP3/CD203c dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ENPP3/CD203c Protéine recombinante Eg2369
• Nom complet: ectonucleotide pyrophosphatase/phosphodiesterase 3
• Masse moléculaire calculée: 875 aa, 100 kDa
• Numéro d’acquisition GenBank: BC146579
• Symbole du gène: ENPP3
• Identification du gène (NCBI): 5169
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

ENPP3, also known as CD203c, is part of ectonucleotide pyrophosphatases/phosphodiesterase (ENPP) family and plays a role in various physiological processes. Increased levels of ENPP3 have been observed in conditions, such as clear cell renal cell carcinoma, bile duct carcinoma, and colorectal cancer, positioning ENPP3 as a potential tumor marker (PMID: 38749434). Mice harboring a point mutant of ENPP3 that specifically abolishes its cGAMP hydrolase activity are more resistant to both primary tumor growth and metastasis in certain cancers (PMID: 38149831).

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