Anticorps Polyclonal de lapin anti-ENPP7

ENPP7 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32226-1-PBS

Synonymes

Alkaline sphingomyelin phosphodiesterase, Alk-SMase, EC:3.1.4.12, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, E-NPP 7

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Galerie de données de validation

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  WB analysis using 32226-1-AP (same clone as 32226-1-PBS)

  Mouse testis tissue lysate was subjected to SDS PAGE followed by western blot with 32226-1-AP (ENPP7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32226-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32226-1-PBS cible ENPP7 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ENPP7 Protéine recombinante Ag36493
• Nom complet: ectonucleotide pyrophosphatase/phosphodiesterase 7
• Masse moléculaire calculée: 51 kDa，458aa
• Poids moléculaire observé: 51 kDa
• Numéro d’acquisition GenBank: NM_178543.4
• Symbole du gène: ENPP7
• Identification du gène (NCBI): 339221
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) stands out as an alkaline sphingomyelinase that functions in the intestine to cleave sphingomyelin (SM) into ceramide and phosphocholine in a phospholipase C (PLC) -like manner and has been associated with hepatobiliary diseases. Reduced ENPP7 activity is detected in colorectal cancer and in familial adenomatous polyposis, suggesting a link between decreased SM metabolism and colon tumorigenesis (PMID: 22177013; 28292932).

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