Anticorps Recombinant de lapin anti-CD39/ENTPD1

CD39/ENTPD1 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241292A1

N° de cat : 84235-4-PBS

Synonymes

ENTPD1, 241292A1, ATP diphosphohydrolase, ATPDase, ATP-DPH

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Galerie de données de validation

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  WB analysis of human placenta using 84235-4-RR (same clone as 84235-4-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 84235-4-RR (ENTPD1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84235-4-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 84235-4-RR (same clone as 84235-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84235-4-RR (ENTPD1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84235-4-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 84235-4-RR (same clone as 84235-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 84235-4-RR (ENTPD1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84235-4-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 84235-4-RR (same clone as 84235-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84235-4-RR (ENTPD1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84235-4-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 84235-4-RR (same clone as 84235-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 84235-4-RR (ENTPD1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84235-4-PBS in a different storage buffer formulation.

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Informations sur le produit

84235-4-PBS cible CD39/ENTPD1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: ectonucleoside triphosphate diphosphohydrolase 1
• Masse moléculaire calculée: 58 kDa
• Poids moléculaire observé: 75 kDa
• Numéro d’acquisition GenBank: BC047664
• Symbole du gène: CD39
• Identification du gène (NCBI): 953
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named CD39, NTPDase 1, and Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. It is a noncovalent tetrameric protein and detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785 ). And it is a 70- to 100-kDa protein that is heavily N-glycosylated(PMID:7930580). This protein has 6 glycosylation sites and 3 isoforms(58 kDa, 59 kDa, and 34 kDa) produced by alternative splicing.

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