Anticorps Polyclonal de lapin anti-EPB41L4B

EPB41L4B Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 31669-1-AP

Synonymes

Band 4.1 like protein 4B, CG1, DKFZp761N1814, EHM2, EPB41L4B, FERM containing protein CG1, FLJ21596, Protein EHM2

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Galerie de données de validation

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  WB analysis using 31669-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31669-1-AP (EPB41L4B antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules Caco-2, cellules HEK-293T, cellules MCF-7, cellules MG U-87

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:5000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

31669-1-AP cible EPB41L4B dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: EPB41L4B Protéine recombinante Ag36353
• Nom complet: erythrocyte membrane protein band 4.1 like 4B
• Masse moléculaire calculée: 99kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: NM_00138562
• Symbole du gène: EPB41L4B
• Identification du gène (NCBI): 54566
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The 4.1 proteins, encoded by the EPB41 (erythrocyte protein band 4.1) genes, are components of the cortical cytoskeleton underlying the cell membrane. The family of 4.1 proteins consists of the eponymous 4.1R protein first identified in erythrocytes (gene: EPB41), 4.1N (EPB41L1), 4.1G (EPB41L2), 4.1B (EPB41L3) as well as the less closely related members NBL4 (EPB41L4A), EHM2 (EPB41L4B) and EPB41L5 (EPB41L5). EHM2 is conspicuous in tumor cells with high migratory potential, such as metastatic melanoma and fibrosarcoma cells. In prostate cancer, EHM2 has been reported to be overexpressed and to diminish adhesion of prostate cancer cells to collagen. (PMID: 20860828)

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