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Anticorps Polyclonal de lapin anti-EPB41L4B

EPB41L4B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31669-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using EPB41L4B Polyclonal antibody (31669-1-AP)

    WB analysis using 31669-1-AP (same clone as 31669-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31669-1-AP (EPB41L4B antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31669-1-PBS in a different storage buffer formulation.

Informations sur le produit

31669-1-PBS cible EPB41L4B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène EPB41L4B Protéine recombinante Ag36353
Nom complet erythrocyte membrane protein band 4.1 like 4B
Masse moléculaire calculée99kDa
Poids moléculaire observé100 kDa
Numéro d’acquisition GenBankNM_00138562
Symbole du gène EPB41L4B
Identification du gène (NCBI) 54566
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The 4.1 proteins, encoded by the EPB41 (erythrocyte protein band 4.1) genes, are components of the cortical cytoskeleton underlying the cell membrane. The family of 4.1 proteins consists of the eponymous 4.1R protein first identified in erythrocytes (gene: EPB41), 4.1N (EPB41L1), 4.1G (EPB41L2), 4.1B (EPB41L3) as well as the less closely related members NBL4 (EPB41L4A), EHM2 (EPB41L4B) and EPB41L5 (EPB41L5). EHM2 is conspicuous in tumor cells with high migratory potential, such as metastatic melanoma and fibrosarcoma cells. In prostate cancer, EHM2 has been reported to be overexpressed and to diminish adhesion of prostate cancer cells to collagen. (PMID: 20860828)

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