Anticorps Recombinant de lapin anti-EPCR/CD201

EPCR/CD201 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241853A7

N° de cat : 98248-1-PBS

Synonymes

Centrosomal protein CCD41, Centrocyclin, CD201, APC receptor, Activated protein C receptor

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Galerie de données de validation

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  FC experiment of bEnd.3 using 98248-1-RR (same clone as 98248-1-PBS)

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug Anti-Mouse EPCR/CD201 Rabbit Recombinant Antibody (98248-1-RR, Clone: 241853A7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98248-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98248-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98248-1-RR against Mouse EPCR/CD201 were performed. The affinity constant is 52.5 pM.

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Informations sur le produit

98248-1-PBS cible EPCR/CD201 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: protein C receptor, endothelial
• Masse moléculaire calculée: 27kDa
• Numéro d’acquisition GenBank: NM_011171.2
• Symbole du gène: PROCR
• Identification du gène (NCBI): 19124
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

EPCR, also known as CD201, protein C receptor (PROCR), or activated protein C receptor (APC receptor), is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).

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