Anticorps Recombinant de lapin anti-EPHX2

EPHX2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251753F4

N° de cat : 86790-1-PBS

Synonymes

Bifunctional epoxide hydrolase 2, CEH, Cytosolic epoxide hydrolase 2, Lipid-phosphate phosphatase, SEH

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Galerie de données de validation

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  WB analysis using 86790-1-RR (same clone as 86790-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86790-1-RR (EPHX2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86790-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86790-1-PBS cible EPHX2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: EPHX2 Protéine recombinante Ag1283
• Nom complet: epoxide hydrolase 2, cytoplasmic
• Masse moléculaire calculée: 63 kDa
• Poids moléculaire observé: 57 kDa
• Numéro d’acquisition GenBank: BC013874
• Symbole du gène: EPHX2
• Identification du gène (NCBI): 2053
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

EPHX2(Epoxide hydrolase 2) acts on epoxides (alkene oxides, oxiranes) and arene oxides and plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. A number of single nucleotide polymorphisms (SNPs) in human EPHX2 have been linked to cardiovascular disease risk, including increased risk of coronary heart disease, hyperlipoproteinemia, and type-2 diabetes (PMID: 14732757, 16595607, 14673705, 15845398, 17460077). It was observed in many tissues with the band of 63 kDa in the western blot. It has also been reported that the N-terminal domain might promote dimerization of EPHX2 (PMID:21553642). Negative expression of EPHX2 protein in U-937 cells is consistent with the predicted expression pattern.

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