Anticorps Polyclonal de lapin anti-EPO/Erythropoietin

• Phare
• Validé par KD/KO

EPO/Erythropoietin Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17908-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of HEK-293 using 17908-1-AP (same clone as 17908-1-PBS)

  WB result of EPO/Erythropoietin antibody (17908-1-AP; 1:300; incubated at room temperature for 1.5 hours) with sh-Control and sh-EPO transfected HEK-293 cells. This data was developed using the same antibody clone with 17908-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 17908-1-AP (same clone as 17908-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 17908-1-AP (EPO/Erythropoietin antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17908-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 17908-1-AP (same clone as 17908-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 17908-1-AP (EPO/Erythropoietin antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17908-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17908-1-PBS cible EPO/Erythropoietin dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: EPO/Erythropoietin Protéine recombinante Ag12302
• Nom complet: erythropoietin
• Masse moléculaire calculée: 193 aa, 21 kDa
• Poids moléculaire observé: 37 kDa
• Numéro d’acquisition GenBank: BC093628
• Symbole du gène: EPO/Erythropoietin
• Identification du gène (NCBI): 2056
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Erythropoietin (Epo) is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin (Epo) is a 166 amino acids protein containing three N-glycosylation sites (Asn-24, Asn-38, and Asn-83) and 1 O- glycosylation site (Ser-126) and involved in the regulation of the level of red blood cells. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. Its effect is realized by binding erythropoietin receptor (EpoR) expressed on erythroid progenitor cells. EpoR, is a glycoprotein expressed on megakaryocytes, erythroid progenitors and endothelial cells. Epo also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.

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