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Anticorps Polyclonal de lapin anti-EPOR

EPOR Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30766-1-PBS

Synonymes

EPO R, EPO-R, erythropoietin receptor

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using EPOR Polyclonal antibody (30766-1-AP)

    WB analysis using 30766-1-AP (same clone as 30766-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30766-1-AP (EPOR antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30766-1-PBS in a different storage buffer formulation.

Informations sur le produit

30766-1-PBS cible EPOR dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène EPOR Protéine recombinante Ag33956
Nom complet erythropoietin receptor
Masse moléculaire calculée55 kDa
Poids moléculaire observé70 kDa
Numéro d’acquisition GenBankNM_000121.4
Symbole du gène EPOR
Identification du gène (NCBI) 2057
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Erythropoietin (EPO) receptor (EPOR) is a glycoprotein that belongs to the type I superfamily of single-transmembrane cytokine receptors. It consists of an extracellular domain that binds to the EPO ligand, a transmembrane domain and an intracellular domain. The interaction of EPO and EPOR triggers the activation of several signaling pathways that induce erythropoiesis, including JAK2/STAT5, PI3K/AKT, and MAPK (PMID: 34281163). EPOR is present on erythroid progenitor cells and has also been detected on a wide variety of non-hematopoietic cells (PMID: 36233351). The calculated molecular weight of EPOR is 55 kDa. EPOR undergoes posttranslational modification and the apparent molecular weight of 66-78 kDa has been reported (PMID: 8943308; 12088257).

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