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Anticorps Recombinant de lapin anti-EPOR

EPOR Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250056D4

N° de cat : 85901-1-PBS

Synonymes

EPO-R, Erythropoietin receptor

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using EPOR Recombinant antibody (85901-1-RR)

    WB analysis using 85901-1-RR (same clone as 85901-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85901-1-RR (EPOR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85901-1-PBS in a different storage buffer formulation.

Informations sur le produit

85901-1-PBS cible EPOR dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

Réactivité souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène EPOR Protéine recombinante Eg2711
Nom complet erythropoietin receptor
Masse moléculaire calculée55 kDa
Poids moléculaire observé73 kDa
Numéro d’acquisition GenBankNM_010149.3
Symbole du gène Epor
Identification du gène (NCBI) 13857
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Erythropoietin (EPO) receptor (EPOR) is a glycoprotein that belongs to the type I superfamily of single-transmembrane cytokine receptors. It consists of an extracellular domain that binds to the EPO ligand, a transmembrane domain and an intracellular domain. The interaction of EPO and EPOR triggers the activation of several signaling pathways that induce erythropoiesis, including JAK2/STAT5, PI3K/AKT, and MAPK (PMID: 34281163). EPOR is present on erythroid progenitor cells and has also been detected on a wide variety of non-hematopoietic cells (PMID: 36233351). The calculated molecular weight of EPOR is 55 kDa. EPOR undergoes posttranslational modification and the apparent molecular weight of 66-78 kDa has been reported (PMID: 8943308; 12088257).

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