Anticorps Polyclonal de lapin anti-EPS15

• Phare
• Validé par KD/KO

EPS15 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31301-1-PBS

Synonymes

AF 1P, AF1P, MLLT5, Protein AF 1p, Protein Eps15

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Galerie de données de validation

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  WB analysis using 31301-1-AP (same clone as 31301-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31301-1-AP (EPS15 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31301-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 31301-1-AP (same clone as 31301-1-PBS)

  WB result of EPS15 antibody (31301-1-AP; 1:12000; incubated at room temperature for 1.5 hours) with sh-Control and sh-EPS15 transfected MCF-7 cells. This data was developed using the same antibody clone with 31301-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31301-1-PBS cible EPS15 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: EPS15 Protéine recombinante Ag35282
• Nom complet: epidermal growth factor receptor pathway substrate 15
• Masse moléculaire calculée: 99 kDa
• Poids moléculaire observé: 140 kDa
• Numéro d’acquisition GenBank: NM_001981.3
• Symbole du gène: EPS15
• Identification du gène (NCBI): 2060
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

EPS15 was originally identified as a substrate for the kinase activity of the epidermal growth factor receptor (EGFR). EPS15 has a tripartite structure comprising an NH2-terminal portion, which contains three EH domains, a central putative coiled-coil region, and a COOH-terminal domain containing multiple copies of the amino acid triplet Aspartate-Proline-Phenylalanine (PMID: 10481267). EPS15 is phosphorylated on tyrosine residues following EGFR activation (PMID: 7689153).

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