Anticorps Monoclonal anti-ERAP2

ERAP2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2B11A2

N° de cat : 67477-1-PBS

Synonymes

ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP

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Galerie de données de validation

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  WB analysis of A549 using 67477-1-Ig (same clone as 67477-1-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 67477-1-Ig (same clone as 67477-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 67477-1-Ig (same clone as 67477-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HSC-T6 using 67477-1-Ig (same clone as 67477-1-PBS)

  HSC-T6 cells were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 67477-1-Ig (same clone as 67477-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67477-1-PBS cible ERAP2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: ERAP2 Protéine recombinante Ag30061
• Nom complet: endoplasmic reticulum aminopeptidase 2
• Masse moléculaire calculée: 110 kDa
• Poids moléculaire observé: 110-120 kDa
• Numéro d’acquisition GenBank: BC065240
• Symbole du gène: ERAP2
• Identification du gène (NCBI): 64167
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ERAP2(Endoplasmic reticulum aminopeptidase 2) is also named as LRAP(Leukocyte-derived arginine aminopeptidase). It plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. ERAP2 can form heterodimers with ERAP1(PMID:15908954). Defects in the expression of ERAP2 may cause improper antigen processing, possibly leading to favor tumor escape from the immune surveillance. ERAP2 has the calculated molecular mass of 105-110 kDa, and apparent molecular mass of 120 kDa duo to the glycosylation.

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