Anticorps Recombinant de lapin anti-ERCC6

ERCC6 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250645D4

N° de cat : 86144-1-PBS

Synonymes

ARMD5, ATP dependent helicase ERCC6, Chimeric CSB-PGBD3 protein, Chimeric ERCC6-PGBD3 protein, CKN2

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Galerie de données de validation

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  WB analysis of HeLa using 86144-1-RR (same clone as 86144-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 86144-1-RR (ERCC6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86144-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86144-1-PBS cible ERCC6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ERCC6 Protéine recombinante Ag18009
• Nom complet: excision repair cross-complementing rodent repair deficiency, complementation group 6
• Masse moléculaire calculée: 1493 aa, 168 kDa
• Poids moléculaire observé: 180 kDa
• Numéro d’acquisition GenBank: BC127104
• Symbole du gène: ERCC6/CSB
• Identification du gène (NCBI): 2074
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ERCC6, also named as CSB, belongs to the SNF2/RAD54 helicase family. It is involved in the preferential repair of active genes. It is presumed DNA or RNA unwinding function. ERCC6 corrects the UV survival and RNA synthesis after UV exposure of Cockayne syndrome complementation group B. Defects in ERCC6 are the cause of Cockayne syndrome type B (CSB) , cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DSC), and UV-sensitive syndrome (UVS). Genetic variation in ERCC6 is associated with susceptibility to age-related macular degeneration type 5 (ARMD5). The antibody is specific to ERCC6.

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