Anticorps Recombinant de lapin anti-ERLIN1

ERLIN1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242778B10

N° de cat : 85377-1-PBS

Synonymes

242778B10, C10orf69, Endoplasmic reticulum lipid raft-associated protein 1, ER lipid raft associated 1, Erlin 1

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Galerie de données de validation

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  WB analysis using 85377-1-RR (same clone as 85377-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85377-1-RR (ERLIN1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85377-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85377-1-PBS cible ERLIN1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ERLIN1 Protéine recombinante Ag11393
• Nom complet: ER lipid raft associated 1
• Masse moléculaire calculée: 346 aa, 39 kDa
• Poids moléculaire observé: 39 kDa
• Numéro d’acquisition GenBank: BC031791
• Symbole du gène: ERLIN1
• Identification du gène (NCBI): 10613
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ERLIN1, also known as Erlin-1 or SPFH1, stands for "ER lipid raft-associated protein 1." It is a protein-coding gene that plays a significant role in cellular processes, particularly in the endoplasmic reticulum (ER). The ER is a crucial organelle involved in protein synthesis, lipid metabolism, and calcium homeostasis. ERLIN1 is part of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) domain-containing family of proteins, which are often associated with lipid rafts-microdomains within cellular membranes that are enriched in cholesterol and sphingolipids. ERLIN1 is involved in the regulation of protein degradation, particularly through the ER-associated degradation (ERAD) pathway (PMID: 37683630).

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