Anticorps Polyclonal de lapin anti-ESPN

ESPN Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20717-1-PBS

Synonymes

LP2654, Espin, DFNB36

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Galerie de données de validation

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  WB analysis using 20717-1-AP (same clone as 20717-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20717-1-AP (ESPN antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20717-1-PBS in a different storage buffer formulation.

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  WB analysis of Neuro-2a using 20717-1-AP (same clone as 20717-1-PBS)

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 20717-1-AP (ESPN antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20717-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 20717-1-AP (same clone as 20717-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 20717-1-AP (ESPN antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20717-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20717-1-PBS cible ESPN dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: espin
• Masse moléculaire calculée: 92 kDa
• Poids moléculaire observé: 30-33 kDa, 110 kDa
• Numéro d’acquisition GenBank: NM_031475
• Symbole du gène: ESPN
• Identification du gène (NCBI): 83715
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ESPN, also named as DFNB36, is a multifunctional actin-bundling protein. ESPN plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells. Defects in ESPN are the cause of deafness autosomal recessive type 36 (DFNB36). Defects in ESPN are the cause of deafness autosomal dominant without vestibular involvement (DFNAWVI). The antibody is specific to ESPN.

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