Anticorps Recombinant de lapin anti-Endoglin/CD105

Endoglin/CD105 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

242305E7

N° de cat : FITC-98290

Synonymes

CD105, 242305E7, Edg, endoglin, Eng

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Galerie de données de validation

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  FC experiment of bEnd.3 using FITC-98290

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug FITC Plus Anti-Mouse Endoglin/CD105 Rabbit RecAb (FITC-98290, Clone: 242305E7) (red) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules bEnd.3

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98290 cible Endoglin/CD105 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Endoglin/CD105 Protéine recombinante Eg1292
• Nom complet: endoglin
• Masse moléculaire calculée: 70 kDa
• Numéro d’acquisition GenBank: NM_007932.2
• Symbole du gène: CD105
• Identification du gène (NCBI): 13805
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

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