Anticorps Recombinant de lapin anti-Endoglin/CD105

Endoglin/CD105 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

241196D9

N° de cat : PE-98013-2

Synonymes

CD105, 241196D9, END, Endoglin, ENG

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Galerie de données de validation

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  FC experiment of human PBMCs using PE-98013-2

  1x10^6 FC receptor blocked human PBMCs were surface stained with 5 ul PE Anti-Human Endoglin/CD105 Rabbit RecAb (PE-98013-2, Clone: 241196D9) or PE Rabbit IgG Isotype Control RecAb (PE-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of human PBMCs using PE-98013-2

  1x10^6 FC receptor blocked human PBMCs were surface stained with 5 ul PE Anti-Human Endoglin/CD105 Rabbit RecAb (PE-98013-2, Clone: 241196D9) (red) or PE Rabbit IgG Isotype Control RecAb (PE-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-98013-2 cible Endoglin/CD105 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Endoglin/CD105 Protéine recombinante Eg0587
• Nom complet: endoglin
• Masse moléculaire calculée: 71 kDa
• Numéro d’acquisition GenBank: BC014271
• Symbole du gène: CD105
• Identification du gène (NCBI): 2022
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodeling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

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