Anticorps Polyclonal de lapin anti-Exportin 4

• Phare
• Validé par KD/KO

Exportin 4 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25373-1-PBS

Synonymes

XPO4, Exp4, Exportin-4, KIAA1721

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Galerie de données de validation

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  WB analysis using 25373-1-AP (same clone as 25373-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25373-1-AP (Exportin 4 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 25373-1-AP (same clone as 25373-1-PBS)

  WB result of Exportin 4 antibody (25373-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-Exportin 4 transfected HEK-293 cells. This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 25373-1-AP (same clone as 25373-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 25373-1-AP (Exportin 4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 25373-1-AP (same clone as 25373-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 25373-1-AP (Exportin 4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25373-1-PBS cible Exportin 4 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Exportin 4 Protéine recombinante Ag21845
• Nom complet: exportin 4
• Masse moléculaire calculée: 1151 aa, 130 kDa
• Poids moléculaire observé: 127 kDa
• Numéro d’acquisition GenBank: BC113571
• Symbole du gène: Exportin 4/XPO4
• Identification du gène (NCBI): 64328
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

exportin 4 (XPO4) maps to chromosome 13q and belongs to the importin β family which acts as a bidirectional nuclear transport receptor. Decreased XPO4 expression has been shown to associate with hepatocellular carcinoma. A genome-wide copy number variation (CNV) association study in a small cohort of Malaysian subjects identified a CNV in XPO4 to be correlated with the progression of metabolic (dysfunction) associated fatty liver disease (MAFLD). (PMID: 34388518)

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