Anticorps Polyclonal de lapin anti-FAAP100

FAAP100 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31841-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 31841-1-AP (same clone as 31841-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31841-1-AP (FAAP100 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31841-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

31841-1-PBS cible FAAP100 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FAAP100 Protéine recombinante Ag36385
• Nom complet: chromosome 17 open reading frame 70
• Masse moléculaire calculée: 93 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: BC117139
• Symbole du gène: C17orf70
• Identification du gène (NCBI): 80233
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FA core complex associated protein 100 (FAAP100, also known as C17orf70) is a component of the Fanconi anemia (FA), which plays a role in the FA-associated DNA damage response network as well as regulates Fanconi anemia group D2 protein (FANCD2) monoubiquitination and the stability of the FA core complex (PMID: 17396147). FAAP100 deletion leads to FA pathway inactivation, increases TRCs and cotranscriptional R-loops, and contributes to the collapse of replication forks and the generation of DNA damage (PMID: 37580696).

{{ptg:RelatedPrimaryAntibodies}}