Anticorps Polyclonal de lapin anti-FAM107A

• Phare
• Validé par KD/KO

FAM107A Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12176-1-PBS

Synonymes

Down-regulated in renal cell carcinoma 1, DRR1, TU3A

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Galerie de données de validation

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  IHC staining of human thyroid cancer using 12176-1-AP (same clone as 12176-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 12176-1-AP (FAM107A antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

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  IHC staining of human thyroid cancer using 12176-1-AP (same clone as 12176-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 12176-1-AP (FAM107A antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 12176-1-AP (same clone as 12176-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using FAM107A antibody (12176-1-AP) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12176-1-PBS cible FAM107A dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FAM107A Protéine recombinante Ag2820
• Nom complet: family with sequence similarity 107, member A
• Masse moléculaire calculée: 144 aa, 17 kDa
• Numéro d’acquisition GenBank: BC010561
• Symbole du gène: FAM107A
• Identification du gène (NCBI): 11170
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FAM107A, also named as TU3A, encodes a 144 amino-acid protein, which contains a coiled-coil domain and a nuclear localization signal. FAM107A as a transcription factor regulates some gene transcription and signal transduction in cell. With the exception of peripheral blood cells, FAM107A is widely expressed in normal tissues, but shows significant loss of expression in renal cell carcinomas and frequent loss of expression in cervical, gastric, ovarian and non small cell lung cancers. Transfection of FAM107A mRNA into cancer cell line inhibits cell growth and proliferation, supporting the evidence that the gene functions as an important tumor suppressor.

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