Anticorps Polyclonal de lapin anti-FAM172A

FAM172A Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24732-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 24732-1-AP (same clone as 24732-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24732-1-AP (FAM172A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24732-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 24732-1-AP (same clone as 24732-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24732-1-AP (FAM172A Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 24732-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 24732-1-AP (same clone as 24732-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24732-1-AP (FAM172A Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 24732-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24732-1-PBS cible FAM172A dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FAM172A Protéine recombinante Ag20437
• Nom complet: family with sequence similarity 172, member A
• Masse moléculaire calculée: 416 aa, 48 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: BC020584
• Symbole du gène: FAM172A
• Identification du gène (NCBI): 83989
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Family with sequence similarity 172 member A (FAM172A), cloned from human aortic tissues, is subsequently observed in human endothelial and vascular smooth muscle cells, and macrophages. As the imbalance of the cell cycle and apoptosis is closely related to the key characteristics of malignant tumors, FAM172A dysregulation is a potential contributing factor in cell transformation. Recently, FAM172A has been reported to take part in the development of several cancers, such as human liver, colorectal and papillary thyroid cancers. Moreover, FAM172A was upregulated by high glucose in a concentration- and time-dependent manner which indicated that FAM172A may be involved in the pathogenesis of diabetic related diseases. FAM172A has 4 isoforms with the molecular mass of 34-36, 43 and 48 kDa. This antibody was detected at 50-55 kDa on SDS-PAGE. (PMID: 31988090, 26637224)

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