Anticorps Polyclonal de lapin anti-FAM76B

FAM76B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32882-1-PBS

Synonymes

Protein FAM76B

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Galerie de données de validation

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  WB analysis using 32882-1-AP (same clone as 32882-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32882-1-AP (FAM76B antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32882-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32882-1-PBS cible FAM76B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FAM76B Protéine recombinante Ag36658
• Nom complet: family with sequence similarity 76, member B
• Masse moléculaire calculée: 39kDa，339aa
• Poids moléculaire observé: 36-39 kDa
• Numéro d’acquisition GenBank: NM_144664.4
• Symbole du gène: FAM76B
• Identification du gène (NCBI): 143684
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FAM76B is a nuclear protein with a molecular weight of about 39 kDa. Its amino acid sequence is highly conserved, and it is highly similar to FAM76B sequence of rats, mice and zebrafish. The protein contains histidine repeat sequence (poly-His domain) and ubiquitination site of Lys-225. FAM76B inhibits the inflammatory reaction mediated by NF-κB by affecting the cytoplasmic translocation of hnRNPA2B1. The expression of inflammatory factors (such as IL-6) increased significantly in FAM76B gene knockout mice, indicating that FAM76B has anti-inflammatory effect.

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