Anticorps Polyclonal de lapin anti-FAM86A

FAM86A Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32472-1-PBS

Synonymes

EC:2.1.1.-, EEF2KMT, eEF2-KMT, eEF2-lysine methyltransferase, Eukaryotic Elongation Factor 2 Lysine Methyltransferase

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Galerie de données de validation

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  WB analysis using 32472-1-AP (same clone as 32472-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32472-1-AP (FAM86A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32472-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32472-1-PBS cible FAM86A dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FAM86A Protéine recombinante Ag38481
• Nom complet: family with sequence similarity 86, member A
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC010084
• Symbole du gène: FAM86A
• Identification du gène (NCBI): 196483
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FAM86A is a class I lysine methyltransferase (KMT), belonging to the family of protein methyltransferases (KMTs), which produces trimethylation (K525me3) at the Lys525 site of eukaryotic translation elongation factor 2 (EEF2) and promotes the binding of eEF2 to ribosomes, thereby regulating the protein synthesis. (PMID: 38508183) FAM86A is expressed in a highly dependent manner in a variety of human cancer cell lines, suggesting that FAM86A may be a potential target for future anticancer therapy.

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