Anticorps Polyclonal de lapin anti-FAM96A

FAM96A Polyclonal Antibody for IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20776-1-PBS

Synonymes

Protein FAM96A, MIP18 family protein FAM96A, Cytosolic iron-sulfur assembly component 2A, CIAO2A, CIA2A

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Galerie de données de validation

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  IP experiment of THP-1 using 20776-1-AP (same clone as 20776-1-PBS)

  IP result of anti-FAM96A (IP:20776-1-AP, 4ug; Detection:20776-1-AP 1:600) with THP-1 cells lysate 2400 ug. This data was developed using the same antibody clone with 20776-1-PBS in a different storage buffer formulation.

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  IP experiment of U-937 using 20776-1-AP (same clone as 20776-1-PBS)

  IP result of anti-FAM96A (IP:20776-1-AP, 4ug; Detection:20776-1-AP 1:600) with U-937 cells lysate 2240 ug. This data was developed using the same antibody clone with 20776-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 20776-1-AP (same clone as 20776-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using FAM96A antibody (20776-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 20776-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20776-1-PBS cible FAM96A dans les applications de IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FAM96A Protéine recombinante Ag14770
• Nom complet: family with sequence similarity 96, member A
• Masse moléculaire calculée: 160 aa, 18 kDa
• Poids moléculaire observé: 18-21 kDa
• Numéro d’acquisition GenBank: BC008865
• Symbole du gène: FAM96A
• Identification du gène (NCBI): 84191
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FAM96A (family with sequence similarity 96, member A), also called cytosolic iron-sulfur assembly component 2A (CIAO2A), a recently identified member of the cytosolic iron-sulfur (Fe/S) protein assembly machinery and regulator of cellular iron homeostasis, is a novel pro-apoptotic APAF1-binding protein facilitating the effective induction of cell death via the mitochondrial apoptosis pathway. FAM96A is substantially enriched in macrophages comprised primarily of a DUF59 domain (residues 31-157) and an N-terminal signal peptide (residues 1-27), that is expressed at low levels in tumor cells (PMID: 29399066).

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