Anticorps Recombinant de lapin anti-FANCA

FANCA Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242600E10

N° de cat : 84923-5-PBS

Synonymes

242600E10, FA, FA1, FAA, FACA

---

Galerie de données de validation

• 

  WB analysis using 84923-5-RR (same clone as 84923-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84923-5-RR (FANCA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84923-5-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84923-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84923-5-RR against Human FANCA were performed. The affinity constant is 0.351 nM.

---

Informations sur le produit

84923-5-PBS cible FANCA dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FANCA Protéine recombinante Ag2598
• Nom complet: Fanconi anemia, complementation group A
• Masse moléculaire calculée: 163 kDa
• Poids moléculaire observé: 163 kDa
• Numéro d’acquisition GenBank: BC008979
• Symbole du gène: FANCA
• Identification du gène (NCBI): 2175
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

FANCA, also named as FAA, FACA and FANCH, is DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is specific to isoform1 of FANCA.

{{ptg:RelatedPrimaryAntibodies}}